Role of estrogen in breast cancer

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Metrics details. Prevention has long been the holy grail of breast cancer research. The significant reduction in breast cancer risk afforded by a full-term pregnancy early in life suggests the great potential of preventive strategies. In contrast to the risks associated with prolonged exposures, exogenous estrogen and progesterone for short durations can mimic the protective effects of pregnancy in carcinogen-induced mammary tumor models.

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How does the estrogen receptor work?

How does the estrogen receptor work? | Breast Cancer Research | Full Text

Taking estrogen may increase a woman's risk of getting breast cancer. The estrogen in a womans body seems to raise breast cancer risk by encouraging the growth of breast tissue, which can speed up an existing tumors growth. Here's what you need to know. It showed that even after the women stopped taking combination HT , their breast cancer risk remained elevated.

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Do estrogen levels increase the risk of breast cancer? Gynaecologist explains

Some types of breast cancer are affected by hormones, like estrogen and progesterone. The breast cancer cells have receptors proteins that attach to estrogen and progesterone, which helps them grow. Treatments that stop these hormones from attaching to these receptors are called hormone or endocrine therapy.

Metrics details. It has long been known that ovarian production of the sex steroid hormone, estrogen, affects growth, differentiation, and function of the mammary gland. By interacting with estrogen-response elements contained in the promoter region of specific genes, modulation of gene expression ultimately results in the biological effects of estrogen.